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There is a clear need for the development of microparticles that can be used simultaneously as carriers of stem/progenitor cells and as release systems for bioactive agents, such as growth factors or differentiation agents. In addition, when thinking on bone-tissue-engineering applications, it would be very useful if these microparticles are biodegradable and could be made to be bioactive. Microparticles...
One of the most promising therapies for symptomatic disc degeneration involves the implantation of therapeutic cells into the degenerative disc.In this article, the rationale and approaches for cell-based tissue engineering of the intervertebral disc are discussed.The scientific literature related to cell-based tissue engineering of the intervertebral disc is reviewed.A variety of cell types have...
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