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The cover image, by James E. Dennis et al., is based on the Research Article Tissue engineering of a composite trachea construct using autologous rabbit chondrocytes, DOI: 10.1002/term.2523. Illustration Credit: Kathleen Wagner and Jordan Peitz.
The repair of large tracheal segmental defects remains an unsolved problem. The goal of this study is to apply tissue engineering principles for the fabrication of large segmental trachea replacements. Engineered tracheal replacements composed of autologous cells (neotracheas) were tested in a New Zealand White rabbit model. Neotracheas were formed in the rabbit neck by wrapping a silicone tube with...
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