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The mechanisms, by which the P2 receptor agonists adenosine 5'-triphosphate (ATP) and uridine 5'-triphosphate (UTP) evoke an increase in the free cytosolic calcium concentration ([Ca 2+ ] i ) and in intracellular pH (pH i ), have been investigated in Ehrlich ascites tumor cells. The increase in [Ca 2+ ] i evoked by ATP or UTP is abolished after depletion...
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