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Designing three‐dimensional (3D) scaffolds for selective manipulation of cell growth is of high relevance for applications in regenerative medicine. Especially, scaffolds with oriented morphologies bear high potential to guide the restoration of specific tissues. The fabrication of hydrogel scaffolds that support long‐term survival, proliferation, and unidirectional growth of embedded cells is presented...
Topographic surface patterning of intrinsically non‐adhesive P(EO‐stat‐PO)‐based hydrogels can lead to the adhesion and spreading of fibroblasts. Explanations for this unexpected behavior are discussed, particularly with regard to non‐specific protein adsorption from the serum‐supplemented culture medium. The presence of serum proteins is shown to be essential for adhesion. Adsorption of plasma and...
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