Search results for: M. Schott

Items from 1 to 20 out of 890 results

article

Predicting progression to Alzheimer's disease dementia using cognitive measures

Amy Macdougall, Tim Whitfield, Kelly Needham, Jonathan M. Schott, more

International Journal of Geriatric Psychiatry > 39 > 2 > n/a - n/a

Objectives It is important to determine if cognitive measures identified as being prognostic in dementia research cohorts also have utility in memory clinics. We aimed to identify measures with the greatest power to predict future Alzheimer's disease (AD) dementia in a clinical setting where expensive biomarkers are not widely available. Methods This study utilized routine Memory Clinic data collected...

article

Blood biomarkers for Alzheimer's disease and related disorders

Henrik Zetterberg, Jonathan M. Schott

Acta Neurologica Scandinavica > 146 > 1 > 51 - 55

Alzheimer's disease (AD) is a progressive neurodegenerative disease and the single commonest cause of dementia. Many other diseases can, however, cause dementia, and differential diagnosis can be challenging, especially in early disease stages. For most neurodegenerative dementias, accumulation of brain pathologies starts many years before clinical onset; the ability to detect these pathologies paves...

article

Amyloid processing in COVID‐19‐associated neurological syndromes

Oliver J. Ziff, Nicholas J. Ashton, Puja R. Mehta, Rachel Brown, more

Journal of Neurochemistry > 161 > 2 > 146 - 157

SARS‐CoV‐2 infection can damage the nervous system with multiple neurological manifestations described. However, there is limited understanding of the mechanisms underlying COVID‐19 neurological injury. This is a cross‐sectional exploratory prospective biomarker cohort study of 21 patients with COVID‐19 neurological syndromes (Guillain–Barre Syndrome [GBS], encephalitis, encephalopathy, acute disseminated...

article

Mild Parkinsonian Signs: A Systematic Review of Clinical, Imaging, and Pathological Associations

Sarah M. Buchanan, Marcus Richards, Jonathan M. Schott, Anette Schrag

Movement Disorders > 36 > 11 > 2481 - 2493

Mild parkinsonian signs (MPS) have been widely studied during the past 3 decades and proposed as a risk marker for neurodegenerative disease. This systematic review explores the epidemiology, clinical and prognostic associations, radiological features, and pathological findings associated with MPS in older adults free from neurodegenerative disease. We find that MPS as currently defined are strongly...

article

Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease

D. O. T. Alawode, A. J. Heslegrave, N. J. Ashton, T. K. Karikari, more

Journal of Internal Medicine > 290 > 3 > 583 - 601

Alzheimer’s disease (AD) is increasingly prevalent worldwide, and disease‐modifying treatments may soon be at hand; hence, now, more than ever, there is a need to develop techniques that allow earlier and more secure diagnosis. Current biomarker‐based guidelines for AD diagnosis, which have replaced the historical symptom‐based guidelines, rely heavily on neuroimaging and cerebrospinal fluid (CSF)...

article

When dementia is misdiagnosed

Robert Howard, Jonathan M. Schott

International Journal of Geriatric Psychiatry > 36 > 6 > 799 - 801

article

A Clinicopathologic Study of Movement Disorders in Frontotemporal Lobar Degeneration

Eduardo Pablo‐Fernández, Belén González‐Herrero, Debora Cerdán Santacruz, Martin N. Rossor, more

Movement Disorders > 36 > 3 > 632 - 641

Background Despite the considerable overlap with atypical parkinsonism, a systematic characterization of the movement disorders associated with frontotemporal lobar degeneration (FTLD) is lacking. Objective The aim of this study is to provide a detailed description of the phenomenology and neuropathologic correlations of movement disorders in FTLD. Methods In this cohort study, movement disorder...

article

Patients' productivity losses and informal care costs related to ischemic stroke: a French population‐based study

M. Barral, H. Rabier, A. Termoz, H. Serrier, more

European Journal of Neurology > 28 > 2 > 548 - 557

Background and purpose Large societal costs of stroke should not be ignored. We aimed to estimate patients' productivity losses and informal care costs during the first year after ischemic stroke. Methods A cross‐sectional survey was performed within the STROKE69 regional population‐based cohort study. At 1 year post‐stroke, each patient and the corresponding main informal caregiver received questionnaires...

article

Motoric cognitive risk syndrome and incident dementia: results from a population‐based prospective and observational cohort study

O. Beauchet, H. Sekhon, C.P. Launay, Y. Rolland, more

European Journal of Neurology > 27 > 3 > 468 - 474

Background and purpose Motoric cognitive risk syndrome (MCR), which is the juncture of subjective cognitive complaint and slow gait speed, is a pre‐dementia stage. The aims of the study are (i) to compare characteristics between individuals who have MCR defined using slow walking speed and/or increased five‐times‐sit‐to‐stand (FTSS) time as its motor component(s); and (ii) to characterize the association...

article

ATLAS b-jet identification performance and efficiency measurement with $$t{\bar{t}}$$ tt¯ events in pp collisions at $$\sqrt{s}=13$$ s=13 TeV

G. Aad, B. Abbott, D. C. Abbott, A. Abed Abud, more

The European Physical Journal C > 2019 > 79 > 11 > 1-36

The algorithms used by the ATLAS Collaboration during Run 2 of the Large Hadron Collider to identify jets containing b-hadrons are presented. The performance of the algorithms is evaluated in the simulation and the efficiency with which these algorithms identify jets containing b-hadrons is measured in collision data. The measurement uses a likelihood-based method in a sample highly enriched in $$t{\bar{t}}$$...

article

Measurement of $$W^\pm $$ W± boson production in Pb+Pb collisions at $$\sqrt{s_{\mathrm{NN}}} = 5.02~\text {Te}\text {V}$$ sNN=5.02Te with the ATLAS detector

G. Aad, B. Abbott, D. C. Abbott, A. Abed Abud, more

The European Physical Journal C > 2019 > 79 > 11 > 1-32

A measurement of $$W^\pm $$ W± boson production in Pb+Pb collisions at $$\sqrt{s_\mathrm {NN}} = 5.02~\text {Te}\text {V}$$ sNN=5.02Te is reported using data recorded by the ATLAS experiment at the LHC in 2015, corresponding to a total integrated luminosity of $$0.49\;\mathrm {nb^{-1}}$$ 0.49nb-1 . The $$W^\pm $$ W± bosons are reconstructed in the electron or muon leptonic decay channels. Production...

article

Measurement of $$W^{\pm }$$ W± -boson and Z-boson production cross-sections in pp collisions at $$\sqrt{s}=2.76$$ s=2.76 TeV with the ATLAS detector

ATLAS Collaboration, G. Aad, B. Abbott, D. C. Abbott, more

The European Physical Journal C > 2019 > 79 > 11 > 1-29

The production cross-sections for $$W^{\pm }$$ W± and Z bosons are measured using ATLAS data corresponding to an integrated luminosity of 4.0 pb$$^{-1}$$ -1 collected at a centre-of-mass energy $$\sqrt{s}=2.76$$ s=2.76 TeV. The decay channels $$W \rightarrow \ell \nu $$ W→ℓν and $$Z \rightarrow \ell \ell $$ Z→ℓℓ are used, where $$\ell $$ ℓ can be an electron or a muon. The cross-sections are...

article

Search for heavy neutral leptons in decays of W bosons produced in 13 TeV pp collisions using prompt and displaced signatures with the ATLAS detector

The ATLAS collaboration, G. Aad, B. Abbott, D. C. Abbott, more

Journal of High Energy Physics > 2019 > 2019 > 10 > 1-47

Abstract The problems of neutrino masses, matter-antimatter asymmetry, and dark matter could be successfully addressed by postulating right-handed neutrinos with Majorana masses below the electroweak scale. In this work, leptonic decays of W bosons extracted from 32.9 fb⁻¹ to 36.1 fb⁻¹ of 13 TeV proton–proton collisions at the LHC are used to search for heavy neutral leptons (HNLs) that are produced...

article

Measurement of fiducial and differential $$W^+W^-$$ W+W- production cross-sections at $$\sqrt{s}=13$$ s=13 TeV with the ATLAS detector

ATLAS collaboration, M. Aaboud, G. Aad, B. Abbott, more

The European Physical Journal C > 2019 > 79 > 10 > 1-34

A measurement of fiducial and differential cross-sections for $$W^+W^-$$ W+W- production in proton–proton collisions at $$\sqrt{s}=13$$ s=13 TeV with the ATLAS experiment at the Large Hadron Collider using data corresponding to an integrated luminosity of 36.1 $$\hbox {fb}^{-1}$$ fb-1 is presented. Events with one electron and one muon are selected, corresponding to the decay of the diboson system...

article

Measurement of the inclusive isolated-photon cross section in pp collisions at s $$ \sqrt{s} $$ = 13 TeV using 36 fb⁻¹ of ATLAS data

The ATLAS collaboration, G. Aad, B. Abbott, D. C. Abbott, more

Journal of High Energy Physics > 2019 > 2019 > 10 > 1-51

Abstract The differential cross section for isolated-photon production in pp collisions is measured at a centre-of-mass energy of 13 TeV with the ATLAS detector at the LHC using an integrated luminosity of 36.1 fb⁻¹. The differential cross section is presented as a function of the photon transverse energy in different regions of photon pseudorapidity. The differential cross section as a function...

article

Measurement of the inclusive cross-section for the production of jets in association with a Z boson in proton–proton collisions at 8 TeV using the ATLAS detector

G. Aad, B. Abbott, D. C. Abbott, O. Abdinov, more

The European Physical Journal C > 2019 > 79 > 10 > 1-47

The inclusive cross-section for jet production in association with a Z boson decaying into an electron–positron pair is measured as a function of the transverse momentum and the absolute rapidity of jets using 19.9 fb$$^{-1}$$ -1 of $$\sqrt{s}=8$$ s=8 TeV proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider. The measured $$Z\text { + jets}$$ Z+ jets cross-section...

article

Identification of boosted Higgs bosons decaying into b-quark pairs with the ATLAS detector at 13 $$\text {TeV}$$ TeV

ATLAS Collaboration, G. Aad, B. Abbott, D. C. Abbott, more

The European Physical Journal C > 2019 > 79 > 10 > 1-38

This paper describes a study of techniques for identifying Higgs bosons at high transverse momenta decaying into bottom-quark pairs, $$H \rightarrow b\bar{b}$$ H→bb¯ , for proton–proton collision data collected by the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy $$\sqrt{s}=13$$ s=13 $$\text {TeV}$$ TeV . These decays are reconstructed from calorimeter jets found with the...

article

Measurement of ZZ production in the ℓℓνν final state with the ATLAS detector in pp collisions at s $$ \sqrt{s} $$ = 13 TeV

The ATLAS collaboration, M. Aaboud, G. Aad, B. Abbott, more

Journal of High Energy Physics > 2019 > 2019 > 10 > 1-48

Abstract This paper presents a measurement of ZZ production with the ATLAS detector at the Large Hadron Collider. The measurement is carried out in the final state with two charged leptons and two neutrinos, using data collected during 2015 and 2016 in pp collisions at s $$ \sqrt{s} $$ = 13 TeV, corresponding to an integrated luminosity of 36.1 fb⁻¹. The integrated cross-sections in the total...

article

Search for excited electrons singly produced in proton–proton collisions at $$\sqrt{s} ~=~13~\text {Te}\text {V}$$ s=13Te with the ATLAS experiment at the LHC

M. Aaboud, G. Aad, B. Abbott, D. C. Abbott, more

The European Physical Journal C > 2019 > 79 > 9 > 1-30

A search for excited electrons produced in pp collisions at $$\sqrt{s}$$ s = 13 $$\text {Te}\text {V}$$ Te via a contact interaction $$q{\bar{q}}\rightarrow ee^*$$ qq¯→ee∗ is presented. The search uses 36.1 fb$$^{-1}$$ -1 of data collected in 2015 and 2016 by the ATLAS experiment at the Large Hadron Collider. Decays of the excited electron into an electron and a pair of quarks ($$eq{\bar{q}}$$...

article

Measurement of the cross-section and charge asymmetry of W bosons produced in proton–proton collisions at $$\sqrt{s}=8~\text {TeV}$$ s=8TeV with the ATLAS detector

G. Aad, B. Abbott, D. C. Abbott, O. Abdinov, more

The European Physical Journal C > 2019 > 79 > 9 > 1-25

This paper presents measurements of the $$W^+ \rightarrow \mu ^+\nu $$ W+→μ+ν and $$W^- \rightarrow \mu ^-\nu $$ W-→μ-ν cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton–proton collisions at a centre-of-mass energy of 8 $$\text {TeV}$$ TeV with the ATLAS experiment at the LHC and correspond to a total...

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INFONA - science communication portal

Search results for: M. Schott

Predicting progression to Alzheimer's disease dementia using cognitive measures

Blood biomarkers for Alzheimer's disease and related disorders

Amyloid processing in COVID‐19‐associated neurological syndromes

Mild Parkinsonian Signs: A Systematic Review of Clinical, Imaging, and Pathological Associations

Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease

When dementia is misdiagnosed

A Clinicopathologic Study of Movement Disorders in Frontotemporal Lobar Degeneration

Patients' productivity losses and informal care costs related to ischemic stroke: a French population‐based study

Motoric cognitive risk syndrome and incident dementia: results from a population‐based prospective and observational cohort study

ATLAS b-jet identification performance and efficiency measurement with $$t{\bar{t}}$$ tt¯ events in pp collisions at $$\sqrt{s}=13$$ s=13 TeV

Measurement of $$W^\pm $$ W± boson production in Pb+Pb collisions at $$\sqrt{s_{\mathrm{NN}}} = 5.02~\text {Te}\text {V}$$ sNN=5.02Te with the ATLAS detector

Measurement of $$W^{\pm }$$ W± -boson and Z-boson production cross-sections in pp collisions at $$\sqrt{s}=2.76$$ s=2.76 TeV with the ATLAS detector

Search for heavy neutral leptons in decays of W bosons produced in 13 TeV pp collisions using prompt and displaced signatures with the ATLAS detector

Measurement of fiducial and differential $$W^+W^-$$ W+W- production cross-sections at $$\sqrt{s}=13$$ s=13 TeV with the ATLAS detector

Measurement of the inclusive isolated-photon cross section in pp collisions at s $$ \sqrt{s} $$ = 13 TeV using 36 fb⁻¹ of ATLAS data

Measurement of the inclusive cross-section for the production of jets in association with a Z boson in proton–proton collisions at 8 TeV using the ATLAS detector

Identification of boosted Higgs bosons decaying into b-quark pairs with the ATLAS detector at 13 $$\text {TeV}$$ TeV

Measurement of ZZ production in the ℓℓνν final state with the ATLAS detector in pp collisions at s $$ \sqrt{s} $$ = 13 TeV

Search for excited electrons singly produced in proton–proton collisions at $$\sqrt{s} ~=~13~\text {Te}\text {V}$$ s=13Te with the ATLAS experiment at the LHC

Measurement of the cross-section and charge asymmetry of W bosons produced in proton–proton collisions at $$\sqrt{s}=8~\text {TeV}$$ s=8TeV with the ATLAS detector

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