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Purpose This phase II single-institution trial of adjuvant thalidomide after cytoreductive surgery (CS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with appendiceal and colorectal malignancies sought to detect an improvement in progression-free survival (PFS) from 7 to 12 months. Methods Eligible patients received CS, HIPEC, and baseline imaging, followed by pretreatment thalidomide...
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