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Topographic surface patterning of intrinsically non‐adhesive P(EO‐stat‐PO)‐based hydrogels can lead to the adhesion and spreading of fibroblasts. Explanations for this unexpected behavior are discussed, particularly with regard to non‐specific protein adsorption from the serum‐supplemented culture medium. The presence of serum proteins is shown to be essential for adhesion. Adsorption of plasma and...
We present a systematic study of a perfluoropolyether (PFPE)-based elastomer as a new biomaterial. Besides its excellent long-term stability and inertness, PFPE can be decorated with topographical surface structures by replica molding. Micrometer-sized pillar structures led to considerably different cell morphology of fibroblasts. Although PFPE is a very hydrophobic material we could show that PFPE...
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