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Aims/hypothesis. Dendritic cells (DCs) are professional antigen presenting cells involved in the initiation of primary immune responses and the preservation of peripheral tolerance. The aim of this study was to develop a DC vaccine for autoantigen-specific prevention of autoimmune diabetes. Methods. Splenocytes from diabetes-prone NOD mice were cultured in conditioned media to obtain a homogeneous...
Aims/hypothesis Dendritic cells (DCs) are professional antigen presenting cells involved in the initiation of primary immune responses and the preservation of peripheral tolerance. The aim of this study was to develop a DC vaccine for autoantigen-specific prevention of autoimmune diabetes. Methods Splenocytes from diabetes-prone NOD mice were cultured in conditioned media to obtain a homogeneous...
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