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Metabolic Glycoengineering
Immune checkpoint ligand functionalized Schwann cells have great potential to treat multiple sclerosis. In article number 2107392, Kin Man Au, Andrew Z. Wang, and Roland Tisch bioengineer Schwann cells functionalized with programmed death ligand 1 (PD‐L1) and cluster of differentiation 86 (CD86) to prevent and ameliorate established mouse models of chronic and relapsing–remitting...
Failure to establish immune tolerance leads to the development of autoimmune disease. The ability to regulate autoreactive T cells without inducing systemic immunosuppression represents a major challenge in the development of new strategies to treat autoimmune disease. Here, a translational method for bioengineering programmed death‐ligand 1 (PD‐L1)‐ and cluster of differentiation 86 (CD86)‐functionalized...
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