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Aims/hypothesis It is well established that diabetes mellitus increases the risk of cardiovascular disease (CVD) and all-cause mortality. Observational studies suggest that a history of diabetic foot ulceration (DFU) may increase this risk further still. We sought to determine to what extent DFU is associated with excess risk over and above diabetes. Methods We identified studies reporting on associations...
Diabet. Med. 28, 1144–1153 (2011)
AbstractAim To quantify global variation in the incidence of lower extremity amputations in light of the rising prevalence of diabetes mellitus.Methods An electronic search was performed using the EMBASE and MEDLINE databases from 1989 until 2010 for incidence of lower extremity amputation. The literature review conformed to Preferred Reporting Items for Systematic...
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