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To assess the association between genetic variants in the ETV5 gene with nonobstructive azoospermia (NOA) associated with Sertoli cell–only (SCO) syndrome.Genetic association study.University.Australian men (65 SCO, 53 NOA, and 242 fertile men) and American men (86 SCO and 54 fertile men).Paraffin-embedded human testicular tissue was sectioned and processed for immunofluorescence. Direct DNA sequencing...
To evaluate heat shock factor Y chromosome (HSFY) mRNA as a biomarker for the presence of retrievable testicular sperm.Case-control study.Academic medical center.Men with nonobstructive azoospermia (NOA).Testicular tissue from men with successful or failed testicular sperm extraction was evaluated with qunatitative real-time polymerase chain reaction (qRT-PCR) for expression of HSFY mRNA.Area under...
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