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Sporulation in Bacillus subtilis is governed by a cascade of alternative RNA polymerase sigma factors. We previously identified a small protein Fin that is produced under the control of the sporulation sigma factor σF to create a negative feedback loop that inhibits σF‐directed gene transcription. Cells deleted for fin are defective for spore formation and exhibit increased levels of σF‐directed gene...
A growing class of proteins regulates transcription through interaction with DNA‐dependent RNA polymerase. Here we report that a recently identified, highly conserved sporulation gene ylyA encodes a novel RNA polymerase‐binding protein that influences the expression of genes under the control of the late‐acting, sporulation sigma factor σG in Bacillus subtilis. Spores from a ylyA mutant exhibited...
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