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ObjectivesTo evaluate the proportion of cardiovascular disease (CVD) incidence that is explained by genetic variation at chromosome 9p21 and to test whether such variation adds incremental information with regard to CVD prediction, beyond traditional risk factors.
Design, setting and participantsrs4977574 on chromosome 9p21 was genotyped in 24 777 subjects from the Malmö Diet and Cancer study who...
Smith JG, Almgren P, Engström G, Hedblad B, Platonov PG, Newton‐Cheh C, Melander O (Department of Cardiology, Lund University, Lund, Sweden; Department of Clinical Sciences, Lund University, Malmö, Sweden; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA; and Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA). Genetic polymorphisms for...
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