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SU5416 shows light-induced reversible geometric isomerism. A simple, reliable, isocratic HPLC method using an UV–vis detector at λ 425nm was developed. The method provides efficient (R S =3.5) analysis of the two isomers with retention of the isomeric integrity. Additionally, the method has linearity over a wide range (50–1000μg/mL, r 2 =0.99), is accurate (99–102%, RSD <4%),...
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