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Aliment Pharmacol Ther 2011; 34: 544–554
SummaryBackground Low thiopurine‐methyl‐transferase (TPMT) activity and high 6‐thioguanine‐nucleotide (6TGN) concentrations have been linked to therapeutic success in inflammatory bowel disease patients treated with thiopurines; however, this has not been implemented in clinical practice.Aim To identify a therapeutic threshold value for TPMT or 6TGN concentrations,...
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