The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
An increasing number of newly developed drugs is poorly soluble in water or simultaneously poorly soluble in water and in organic liquids. In general the bioavailability of these drugs is very poor after oral administration. Parenteral application via the intramuscular route is also not able to reach sufficient blood levels because of the low volume of fluid at the injection site. Intravenous injection...
Poorly soluble drugs with a low bioavailability can be formulated as nanosuspensions for oral (buccal, sublingual) peroral and parenteral (especially i.v.) administration. Nanosuspensions of drugs can be produced by high pressure homogenisation of a drug suspension in aqueous surfactant solutions. The cavitation and the shear forces are strong enough to disrupt the microparticles to nanoparticles...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.