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Objectives
The primary aim of this study was to compare the screening performance for trisomy 21 (T21) between combined first‐trimester screening (cFTS) with referral for invasive testing at a T21 risk ≥ 1 in 300, and contingent screening consisting of referral for invasive testing at a cFTS‐T21 risk ≥ 1 in 100 and referral for cell‐free DNA (cfDNA) testing at a cFTS‐T21 risk between 1 in 100 and...
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