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We present the design of a novel 8 channels system for time resolved optical tomography based on Silicon Photomultipliers (SiPMs), therefore knocking down cost and complexity of this technique and paving the way to a widespread diffusion. We validated the system performances on phantoms.
We characterized the single-photon timing response function of various silicon photomultipliers (SiPMs) over a broad (500–1100 nm) spectral range. We selected two SiPM manufacturers, and we investigated two active areas, i.e., a small (1–1.69 $\hbox{mm}^{2}$) and a large (9 $\hbox{mm}^{2} $) one, for each of them. We demonstrate that selected SiPMs are suitable for time-resolved diffuse optics (DO)...
Time-resolved diffuse optical spectroscopy (TRS) is a valuable technique for the characterization of a variety of diffusive media like biological tissues, fruit, wood and pharmaceutical tablets. The technique is based on the injection of a short pulse (∼ps) on the surface of the sample. The time-of-flight distribution (TOF) of photons detected on a different location of the surface gives information...
Light is strictly connected with life, and its presence is fundamental for any living environment. Thus, many biological mechanisms are related to light interaction or can be evaluated through processes involving energy exchange with photons. Optics has always been a precious tool to evaluate molecular and cellular mechanisms, but the discovery of lasers opened new pathways of interactions of light...
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