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The study of neonatal gender differences in pain expression is important since neonatal pain behavior occurs prior to any learned reaction pattern. The objective of this study was to verify the presence of gender differences in pain expression in preterm and term newborn infants. Sixty-five consecutive neonates (37 female and 28 male infants) with gestational age between 28 and 42 weeks and with 25-120...
Objective: To study the responses of ventilated preterm neonates to a single dose of opioid. Study design: In a randomized, double-blind, controlled trial, 22 mechanically ventilated preterm infants (≤32 weeks) were observed before medication and at 30 and 60 minutes after administration of fentanyl (3 μg/kg) or placebo. Heart rate, blood pressure, arterial blood gases, ventilator settings, and behavioral...
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