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Wounds and the subsequent formation of scars constitute a unified and complex phased process. Effective treatment is crucial; however, the diverse therapeutic approaches for different wounds and scars, as well as varying treatment needs at different stages, present significant challenges in selecting appropriate interventions. Microneedle patch (MNP), as a novel minimally invasive transdermal drug...
Current fish collagen hemostasis for wound healing products is commonly obtained by electrospinning or artificial cross‐linking fish collagen fibers which lacks mechanical properties, and biofunctions. Here, a new bio‐active fish skin scaffold (FSS) is shown using in situ cross‐linked scaleless freshwater fish skin adding adipose‐derived stem cells (ASCs)‐produced exosomes for hemostasis and wound...
Combinational Photothermal‐Immunotherapy
In article number 2206441, Longjiang Zhang, Peng Huang, Zhongqiu Wang, and co‐workers load dual‐immune inhibitors nanomodulators for combinational photothermal‐immunotherapy through regulating abnormal enzymatic metabolism of IDO, blocking PD‐L1/PD‐1 and CD47/SIRPα to reverse immunosuppressive tumor microenvironment, and prevent tumor growth and re‐challenge...
Although photothermal therapy (PTT) can noninvasively kill tumor cells and exert synergistic immunological effects, the immune responses are usually harmed due to the lack of cytotoxic T cells (CTLs) pre‐infiltration and co‐existing of intricate immunosuppressive tumor microenvironment (TME), including the programmed cell death ligand 1 (PD‐L1)/cluster of differentiation 47 (CD47)/regulatory T cells...
A parallel double helix wire‐shaped supercapacitor protocol has been developed by H. Li, T. Zhai and co‐workers, presented on page 1024. Two symmetric titanium@MnO2 fiber electrodes are wound on a flexible nylon fiber by a simple and reliable process. Due to rational structure design, the devices demonstrate excellent mechanical and electrochemical stability under both static and dynamic deformations...
Wire‐shaped flexible supercapacitors (SCs) have aroused much attention due to their small size, light weight, high flexibility, and deformability. However, the previously reported wire‐shaped SCs usually involve complex assembly processes, encounter potential structural instabilities, and the influence of dynamic bending on the electrochemical stability of wire‐shaped SCs is also not clear. Here,...
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