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Inspired by the macromolecular weapons used by a type of white blood cell to capture and kill bacteria, in article number 1807436, J. Scott VanEpps, Shuichi Takayama, and co‐workers engineer nanofibrillar microwebs composed of DNA and histones that mimic neutrophil extracellular traps (NETs). The microwebs can enhance the killing activity of a last‐resort antibiotic against Escherichia coli even when...
Neutrophil extracellular traps (NETs) are decondensed chromatin networks released by neutrophils that can trap and kill pathogens but can also paradoxically promote biofilms. The mechanism of NET functions remains ambiguous, at least in part, due to their complex and variable compositions. To unravel the antimicrobial performance of NETs, a minimalistic NET‐like synthetic structure, termed “microwebs,”...
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