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Background
Bone metastases are frequent in patients with cancer. Electrochemotherapy (ECT) is a minimally invasive treatment based on a high‐voltage electric pulse combined with an anticancer drug. Preclinical and clinical studies supported the use of ECT in patients with metastatic bone disease, demonstrating that it does not damage the mineral structure of the bone and its regenerative capacity,...
Electroporation in the cell membrane occurs following exposure to a high-intensity electric field. Electroporation can be used to introduce large molecules into the cell or to induce cell apoptosis by the application of the electric field alone, provided that the cell damage is such that it cannot be recovered. Electroporation use in clinical practice is standardized in association with drugs, electrochemotherapy,...
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