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Exploring highly efficient, portable, and robust biocatalysts is a great challenge in colorimetric biosensors. To overcome the challenging states in creating single‐atom biocatalysts, such as insufficient activity and stability, here, this work has engineered a unique CeO2 support as nanoglue to tightly anchor the Ru single‐atom sites (CeO2‐Ru) with strong electronic coupling for achieving highly...
Owing to their rich surface chemistry, high conductivity, tunable bandgap, and thermal stability, structured 2D transition‐metal carbides, nitrides, and carbonitrides (MXenes) with modulated atomic environments have emerged as efficient electrochemical energy conversion systems in the past decade. Herein, the most recent advances in the engineering of tunable structured MXenes as a powerful new platform...
Developing efficient, durable, and low‐cost earth‐abundant elements‐based oxygen evolution reaction (OER) catalysts by rapid and scalable strategies is of great importance for future sustainable electrochemical hydrogen production. The earth‐abundant high‐valency metals, especially vanadium, can modulate the electronic structure of 3d metal oxides and oxyhydroxides and offer the active sites near‐optimal...
Delivery System for microRNA
In article number 2104359, Xiaoxiao Cai and co‐workers present a tetrahedral framework nucleic acids‐based delivery system for miRNA. miRNA is protected extracellularly, and efficiently released in response to intracellular RNase after cellular entrance. Similarly, Chinese philosophy “Chuang Tzu” portrayed the transformation of the legendary fish “Kun” (protected microRNA)...
MicroRNAs (miRs) play an important role in regulating gene expression. Limited by their instabilities, miR therapeutics require delivery vehicles. Tetrahedral framework nucleic acids (tFNAs) are potentially applicable to drug delivery because they prominently penetrate tissue and are taken up by cells. However, tFNA‐based miR delivery strategies have failed to separate the miRs after they enter cells,...
To deal with the ever‐growing toxic benzene‐derived compounds in the water system, extensive efforts have been dedicated for catalytic degradation of pollutants. However, the activities and efficiencies of the transition metal‐based nanoparticles or single‐atom sites are still ambiguous in Fenton‐like reactions. Herein, to compare the Fenton‐like catalytic efficiencies of the nanoparticles and single...
Tetrahedral framework nucleic acids (tFNAs) can accelerate the proliferation and migration of human corneal epithelial cells (HCECs), which are important processes of corneal epithelial wound healing. In article number 1901907, Yunfeng Lin and co‐workers show through in vivo experiments that tFNAs can also promote wound healing of a rabbit corneal alkali burn. Thus, tFNAs are promising nanomaterials...
Poor post‐traumatic wound healing can affect the normal function of damaged tissues and organs. For example, poor healing of corneal epithelial injuries may lead to permanent visual impairment. It is of great importance to find a therapeutic way to promote wound closure. Tetrahedral framework nucleic acids (tFNAs) are new promising nanomaterials, which can affect the biological behavior of cells....
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