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Growing evidence suggests that Ca 2+ overload is one of the major contributors of myocardial ischemia/reperfusion-induced injury. Since Frizzled-2 receptor, a seven transmembrane protein, transduces downstream signaling by specialized binding of Wnt5a to increase intracellular Ca 2+ release, this work aimed to investigate the effect of Frizzled-2 on Ca 2+ accumulation in H9c2...
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