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Metabolomics has emerged as a key technique of modern life sciences in recent years. Two major techniques for metabolomics in the last 10 years are gas chromatography coupled to mass spectrometry (GC–MS) and liquid chromatography coupled to mass spectrometry (LC–MS). Each platform has a specific performance detecting subsets of metabolites. GC–MS in combination with derivatisation has a preference...
Metabolomics emerges as one of the cornerstones in systems biology by characterizing metabolic activities as the ultimate readout of physiological processes of biological systems thereby linking genotypes with the corresponding phenotypes. As metabolomics data are high-dimensional, statistical data analysis is complex. No single technique for statistical analysis and biological interpretation of these...
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