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A series of Locusta adipokinetic hormone I (AKH-I), <QLNFTPNWGTa, analogues were synthesized with modifications at the C-terminal threonine residue using a combination of solid- and liquid-phase methodology and evaluated in Locusta migratoria, in a lipid mobilization assay in vivo and an acetate uptake assay in vitro. Modifications at Thr 10 of AKH-I involved replacement of its C-terminal...
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