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Background and Aims
Ras‐like (Ral) small guanosine triphosphatases (GTPases), RalA and RalB, are proto‐oncogenes directly downstream of Ras and cycle between the active guanosine triphosphate‐bound and inactive guanosine diphosphate‐bound forms. RalGTPase‐activating protein (RalGAP) complex exerts a negative regulation. Currently, the role of Ral up‐regulation in cancers remains unclear. We aimed...
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