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Background
This study investigated the natural progression of β‐cell function in Chinese autoimmune type 1 diabetic (T1D) patients and clarified factors possibly influencing the course of the disease.
Methods
The natural progression of β‐cell function of 325 newly diagnosed Chinese autoimmune T1D patients was assessed by fasting and postprandial C‐peptide (FCP and PCP, respectively) levels. β‐Cell...
Type 1 diabetes (T1D) results from a chronic autoimmune process that leads to β‐cell destruction and exogenous insulin dependence. The natural history of T1D proposed by Eisenbarth suggested six relatively independent stages over the course of the entire disease process, which was considered to be linear and chronic. Based on this classical theory, immunotherapies aim to prevent or reverse all these...
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