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Cytomegalovirus (CMV) is a suggested risk factor for chronic allograft nephropathy, and transforming growth factor-β (TGF-β) is a key fibrogenic molecule in this process. CMV has been shown to induce the expression of TGF-β and several cytokines. We analyzed the impact of CMV on urinary excretion of TGF-β, ICAM-1, TNF-α and correlated findings with biopsy histology.Urine samples from 46 renal transplant...
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