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Background
Children with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) are at increased risk of treatment‐related morbidity and mortality compared to non‐DS‐ALL, requiring increased supportive care. We examined the healthcare utilization and costs in DS‐ALL patients to inform future evaluations of novel therapies.
Methods
A provincial registry identified all children (1–17 years) diagnosed...
Background
Children with leukemia and Down syndrome (DS) are at higher risk of acute treatment toxicities than those without DS. Whether late toxicity risks are also elevated is unknown.
Methods
The authors identified all patients diagnosed with leukemia before the age of 18 years in Ontario, Canada between 1987 and 2013 and who survived greater than 5 years since their last pediatric cancer event...
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