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What's known on the subject? and What does the study add?Localization of PDE9 in human LUT has not been reported in the literature, although PDE5 was reported to be abundantly present only in smooth muscle cells using immunohistochemistry.This is the first reported study which demonstrated the expression of PDE9 in the urothelium and neuron cells in the intramural ganglia of human LUT. Patterns of...
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