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Bacterial meningitis is still a life-threatening disease, and early diagnosis of pathogen can be crucial to improving survival rate. Using the surface-enhanced Raman scattering (SERS) platform developed by our group, the pathogens can be differentiated on the basis of their SERS spectra which are believed to related to their surface chemical components. We collected the SERS spectra of ten pathogens:...
A multiscale approach for peak identification and representation is proposed in the context of surface-enhanced Raman spectroscopy (SERS). The issue of overlapping effects, which frequently appear in biological signals but have not been addressed well in established approaches, is the main concern in this paper. The peak identification will be an ambiguous problem if the overlapping effects are not...
A multiscale approach for peak representation and identification is proposed in the context of surface-enhanced Raman spectroscopy (SERS). The SERS spectrum is naturally composed of peaks with different preferred scales, and some tiny but reproducible peaks can be important distinguishing factors. However, if only a single scale is employed, there is a significant probability that a tiny peak will...
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