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Here we report a histone deacetylase (HDAC) inhibitor named DWP0016, which exhibits anti-neuroblastoma potential in vitro. DWP0016 effectively inhibited proliferation of neuroblastoma SH-SY5Y cells at submicromolar levels but did not affect the growth of normal cells. Flowcytometry analysis showed DWP0016 arrested cell cycle at G 1 phase and induced apoptosis in SH-SY5Y cells dose-dependently...
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