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Objective
The Alzheimer's continuum is biologically defined by beta‐amyloid deposition, which at the earliest stages is superimposed upon white matter degeneration in aging. However, the extent to which these co‐occurring changes is characterized is relatively underexplored. The goal of this study was to use diffusional kurtosis imaging (DKI) and biophysical modeling to detect and describe amyloid‐related...
Restrengthening of the residual language network is likely to be crucial for speech recovery in poststroke aphasia. Eight participants with chronic aphasia received intensive speech therapy for 3 weeks, with standardized naming tests and brain magnetic resonance imaging before and after therapy. Kurtosis‐based diffusion tensor tractography was used to measure mean kurtosis (MK) along a segment of...
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