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Background
Aspergillus fumigatus‐specific IgG estimation is crucial for diagnosing allergic bronchopulmonary aspergillosis (ABPA). A point‐of‐care LDBio immunochromatographic lateral flow assay (LFA) had 0%–90% sensitivity to detect IgG/IgM antibodies against A. fumigatus.
Objective
To assess the accuracy of LDBio‐LFA in diagnosing ABPA, using the modified ISHAM‐ABPA working group criteria as the...
Background
The diagnosis of Aspergillus‐sensitised asthma (ASA) and allergic bronchopulmonary aspergillosis (ABPA) is made using IgE against crude antigens of A fumigatus (cAsp). However, the IgE against cAsp has limitations due to cross‐reactivity with other fungi.
Objective
To evaluate the utility of recombinant Afumigatus (rAsp) antigens in detecting ASA and their role in differentiating true...
Background
The role of recombinant A. fumigatus (rAsp) antigens in the diagnosis of allergic bronchopulmonary aspergillosis (ABPA) has not been systematically evaluated. Herein, we evaluate the utility of recombinant A. fumigatus (rAsp) antigens in diagnosing ABPA.
Methods
We systematically reviewed the PubMed, EmBase and Scopus databases for studies evaluating rAsp antigens in ABPA. The QUADAS‐2...
Vitamin D deficiency is believed to be a pathogenetic factor in patients with allergic bronchopulmonary aspergillosis (ABPA) and cystic fibrosis. Whether vitamin D deficiency is also prevalent in ABPA complicating asthma, remains unknown. Herein, we evaluated vitamin D levels in asthmatic patients with and without ABPA. In a prospective study, plasma vitamin D (25[OH]D) levels were measured in consecutive...
Few studies have evaluated the utility of Aspergillus fumigatus‐specific IgG in allergic bronchopulmonary aspergillosis (ABPA). Herein, we evaluate the role of specific IgG in diagnosis and monitoring treatment response in ABPA. Forty‐eight control subjects with A. fumigatus‐associated asthma underwent A. fumigatus‐specific IgG measurements at baseline, while specific IgG was assayed in 102 treatment‐naïve...
The role of total and specific IgE in monitoring treatment responses in allergic bronchopulmonary aspergillosis (ABPA) remains poorly studied. Here in, we evaluate the utility of total and Aspergillus fumigatus specific IgE in the follow‐up of ABPA. Eighty‐one consecutive treatment‐naïve patients of ABPA (acute stage) with pulmonary infiltrates and bronchiectasis underwent measurement of total and...
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