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BACKGROUND AND PURPOSE
Multiple sclerosis (MS) clinical management is based upon lesion characterization from 2‐dimensional (2D) magnetic resonance imaging (MRI) views. Such views fail to convey the lesion‐phenotype (ie, shape and surface texture) complexity, underlying metabolic alterations, and remyelination potential. We utilized a 3‐dimensional (3D) lesion phenotyping approach coupled with imaging...
BACKGROUND AND PURPOSE
There remains a need to further refine the ability of clinicians to differentiate multiple sclerosis (MS) from other disease etiologies. Here, we illustrate the value of 3‐dimensional (3D) geometric shape and surface lesion characteristics between disease states.
METHODS
Standardized 3‐Tesla 3D brain magnetic resonance imaging studies were performed on enrolled MS and nonspecific...
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