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Based on our previous Phase I and II studies of deferoxamine alone and in combination with the cytotoxic agents cytoxan, etoposide, carboplatin, and thiotepa, starting on December 1989, 15 patients with advanced neuroblastoma (NB) entered a pilot study (Am J Clin Oncol 15:319;1992). In 1992 we initiated a single-arm AIEO NB92 multicentric trial for patients with high-risk Stage III and intermediate...
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