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AimHydrogen sulphide (H2S) is endogenously produced and plays an important role as a modulator of neuronal functions; however, its modulatory role in the central CO2 chemoreception is unknown. The aim of the present study was to assess the role of endogenously produced H2S in the ventilatory response to hypercapnia in adult conscious rats.
MethodsCystathionine β‐synthase (CBS) and cystathionine γ...
AimWe hypothesized that hydrogen sulphide (H2S), acting specifically in the anteroventral preoptic region (AVPO – an important integrating site of thermal and cardiorespiratory responses to hypoxia in which H2S synthesis has been shown to be increased under hypoxic conditions), modulates the hypoxic ventilatory response.
MethodsTo test this hypothesis, we measured pulmonary ventilation () and...
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