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Aim
The transcriptional cofactor receptor‐interacting protein 140 (RIP140) is known as a deleterious regulator of cardiac mitochondrial function and energy metabolic homeostasis. This study revealed that RIP140 repressed Sirtuin 3 (SIRT3), a mitochondrial deacetylase that plays an important role in regulating cardiac function.
Methods
RIP140 was overexpressed by adenovirus infection or was knocked...
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