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We propose a new approach for surface plasmon-enhanced fluorescence spectroscopy (SPFS) biosensor with efficient collecting of molecular analytes from a sample at the sensor surface. It is based on a responsive hydrogel binding matrix that is tethered on a metallic sensor surface and that can reversibly swell and collapse upon triggering by an external stimulus. The swelling is associated with a rapid...
In this paper, long range surface plasmons (LRSP) and magnetic iron oxide nanoparticle (MNP) immunoassay are investigated for advancing the sensitivity of surface plasmon resonance (SPR) biosensor technology for the analysis of bacterial pathogens. The MNPs-antibody conjugates served as labels for enhancing the binding-induced refractive index changes and as “vehicles” for rapid delivery of bacteria...
A biosensor scheme that employs long range surface plasmons (LRSPs) for the efficient excitation and collection of fluorescence light from fluorophore-labeled biomolecules captured in a three-dimensional hydrogel matrix is discussed. This new approach to plasmon-enhanced fluorescence (PEF) is experimentally and theoretically investigated by using the Kretschmann configuration of attenuated total reflection...
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