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Objective To investigate the natural history of fast developing esophageal and cardia precursors. Methods Repetitive endoscopic screenings were performed among 40–69-year-olds in the high-incidence areas for esophageal cancer in Shexian. Results The initial diagnosis and the lag-time for 7 subsequently identified severe dysplasia (SD) subjects were as follows: in one subject 13 months after a...
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