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Compositional alteration of the gut microbiota is associated with ulcerative colitis (UC). Here, a model culture system is established for the in vitro human colonic microbiota of UC, which will be helpful for determining medical interventions. 16S ribosomal RNA sequencing confirms that UC models are successfully developed from fecal inoculum and retain the bacterial species biodiversity of UC feces...
We investigated the effect of α‐cyclodextrin (α‐CD) on the bacterial populations of gut microbiota, production of organic acids, and short‐chain fatty acids (SCFAs), and lipid metabolism in obese mice induced by feeding a high‐fat diet (HFD). Male C57BL/6J mice were assigned to three diet groups: normal diet (ND) (5% [w/w] fat), HFD (35% [w/w] fat), and HFD (35% [w/w] fat) + 5.5% (w/w) α‐CD for 16...
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