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Low‐Dose NIR‐II Preclinical Bioimaging
Liposome‐cyanine dyes with enhanced brightness are fabricated by restricting the dyes into the hydrophobic pockets of lipids, enabling low‐dose and NIR‐II dual‐color in vivo imaging. Moreover, uniform biocompatible probes with high brightness are obtained on a large scale according to this strategy, enabling image‐guided tumor surgery in rabbit models and facilitating...
Fluorescence imaging in the second near‐infrared window (NIR‐II, 1000–1700 nm) provides a powerful tool for in vivo structural and functional imaging in deep tissue. However, the lack of biocompatible contrast agents with bright NIR‐II emission has hindered its application in fundamental research and clinical trials. Herein, a liposome encapsulation strategy for generating ultrabright liposome‐cyanine...
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