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Global efforts have been made in the past two decades to efficiently manipulate and assemble tiny entities at micro-scale or even nano-scale. In this paper, we discuss our team's development of adding an interactive controller to the emerging optically-induced dielectrophoresis (ODEP) platform which could be used to rapidly and parallelly manipulate micro and nano particles in fluidic medium. We have...
This study reports an approach to dynamically separate cultured human B-lymphoma (Raji) cells from normal human red blood cells (RBCs), mixed in an isotonic solution, by utilizing a hydrogenated amorphous silicon-based optically-induced electrokinetics chip. A theoretical calculation of the polarization model for the two different types of cells is first presented. The differential velocity between...
This paper presents our discovery that self-rotation of Melan-a pigment cells can be induced by applying appropriate optical dielectrophoretic (ODEP) parameters. Under optically induced DEP force, which is generated by specific optical electrode patterns and with a band-width of AC bias frequencies, Melan-a cells can be trapped or repelled away from the optical electrodes. In addition, the self-rotation...
We have developed a simple, inexpensive and flexible method to automatically manipulate and assemble micro-/nano-entities using optically-induced dielectrophoretic (ODEP) force. Instead of using traditional fixed metal microelectrodes to generate non-uniform electric field, dynamic optical images designed by an animator software and projected through a microscope lens are used as “virtual electrodes”...
This paper presents a theoretical investigation to evaluate and compare the capabilities of using dielectrophoresis (DEP) and optical image-driven dielectrophoresis (ODEP) forces for micro/nano scale manipulation. A simplified model of particle velocity as a function of electrode size and particle radius was derived based on Stokes' law. Then, electric field analysis of two typical electrode configurations...
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