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Antioxidant systems are fundamental components of host–parasite interactions, and often play a key role in parasite survival. Here, we report the cloning, heterologous expression, and characterization of a thioredoxin glutathione reductase (TGR) from Fasciola hepatica. The deduced polypeptide sequence of the cloned open reading frame (ORF) confirmed the experimental N-terminus previously determined...
Salazar-Calderón, M., Martín-Alonso, J. M., Ruiz de Eguino, A. D., Casais, R., Marín, M. S., and Parra, F. 2000. Fasciola hepatica: Heterologous expression and functional characterization of a thioredoxin peroxidase. Experimental Parasitology95, 63–70. A Fasciola hepatica cDNA clone of 779 bp was isolated from an adult worm cDNA expression library by immunological screening using a rabbit serum against...
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