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Objective To evaluate the efficacy and safety of Heyan Kuntai Capsule (和颜坤泰胶囊, HYKT) and hormone therapy (HT) on perimenopausal syndromes (PMSs). Methods From 2005 to 2008, 390 women with PMSs were recruited from 4 clinic centers. The inclusion criteria included ages 40 to 60 years, estradiol (E2) below 30 ng/L, and follicle stimulating hormone (FSH) above 40 IU/L, etc. The patients were randomly...
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