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Glycosylation is one of the most important post-translation modifications steps in eukaryotic cell. In this paper, we propose a new approach based on independent component analysis (ICA) for prediction O-linked glycosylation site and pattern analysis. Principal component analysis (PCA) is first used to find significant uncorrelated components, and then ICA is used to extract independent components...
Predicting protein folding rate is useful for understanding protein folding process and guiding protein design. Most previous methods of predicting folding rate require the tertiary structure of a protein as an input. And most methods do not distinguish the different kinetic natures (two-state folding and multi-state folding) of the proteins. Here we developed a method, SeqRate, to predict both protein...
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