Search results for: Arezoo Saadati

Items from 1 to 9 out of 9 results

article

Reliable recognition of DNA methylation using bioanalysis of hybridization on the surface of Ag/GQD nanocomposite stabilized on poly (β‐cyclodextrin): A new platform for DNA damage studies using genosensor technology

Mina Adampourezare, Arezoo Saadati, Mohammad Hasanzadeh, Gholamreza Dehghan, more

Journal of Molecular Recognition > 35 > 2 > n/a - n/a

Due to the role of DNA methylation in causing cancer in the present study, an innovative and inexpensive method was designed for the sensitive detection of DNA methylation. The silver‐graphene quantum dots (Ag/GQDs) nano ink with high electrical conductivity was used as a substrate for genosensor fabrication toward identification of DNA hybridization. Also, poly (β‐cyclodextrin) (p[β‐CD]) has been...

article

Electrochemical immunoplatform to assist in the diagnosis of oral cancer through the determination of CYFRA 21.1 biomarker in human saliva samples: Preparation of a novel portable biosensor toward non‐invasive diagnosis of oral cancer

Fahimeh Bageri Tofighi, Arezoo Saadati, Houman Kholafazad‐kordasht, Fatemeh Farshchi, more

Journal of Molecular Recognition > 34 > 12 > n/a - n/a

In this study, a novel, low‐cost, and flexible paper‐based electrochemical immunosensor was developed for the bioanalysis of Cyfra 21.1 biomarker in human saliva samples by using stabilization of synthesis Ag nano‐ink on the surface of paper using pen‐on‐paper technology. The employed electrochemical techniques for the evaluation of immunoplatform performance were differential pulse voltammetry and...

article

Trifluralin recognition using touch‐based fingertip: Application of wearable glove‐based sensor toward environmental pollution and human health control

Fatemeh Farshchi, Arezoo Saadati, Houman Kholafazad‐Kordasht, Farzad Seidi, more

Journal of Molecular Recognition > 34 > 11 > n/a - n/a

Monitoring of herbicides and pesticides in water, food, and the environment is essential for human health, and this requires low‐cost, portable devices for widespread deployment of this technology. For the first time, a wearable glove‐based electrochemical sensor based on conductive Ag nano‐ink was developed for the on‐site monitoring of trifluralin residue on the surface of various substrates. Three...

article

A stretchable glove sensor toward rapid monitoring of trifluralin: A new platform for the on‐site recognition of herbicides based on wearable flexible sensor technology using lab‐on‐glove

Mansour Mahmoudpour, Arezoo Saadati, Mohammad Hasanzadeh, Houman Kholafazad‐kordasht

Journal of Molecular Recognition > 34 > 10 > n/a - n/a

In this study, a flexible glove‐based electrochemical sensor as a wearable point‐of‐use screening tool has been fabricated for defense and food security applications. To design the wearable glove‐based sensor, we drew conductive patterns on the fingers of a rubber glove via gold@silver‐modified graphene quantum dots (Au@Ag core‐shell/graphene quantum dots [GQDs]) nano‐ink with optimal thickness. Then,...

article

Chemical binding of pyrrolidinyl peptide nucleic acid (acpcPNA‐T9) probe with AuNPs toward label‐free monitoring of miRNA‐21: A novel biosensing platform for biomedical analysis and POC diagnostics

Nazanin Fathi, Arezoo Saadati, Mohammad Hasanzadeh, Mohammad Samiei

Journal of Molecular Recognition > 34 > 8 > n/a - n/a

miRNAs are attractive factors in cancer research studies due to their important roles for regulating of gene expression. Because of miRNA‐21 expression surplus in many types of cancers, so accurate identification is important. Increasing efforts have caused different methods to improve the sensitivity and specificity of detection. Present study is an attempt to report a new electrochemical label‐free...

article

Recent progress and challenges on the bioassay of pathogenic bacteria

Parinaz Babaie, Arezoo Saadati, Mohammad Hasanzadeh

Journal of Biomedical Materials Research Part B: Applied Biomaterials > 109 > 4 > 548 - 571

The present review (containing 242 references) illustrates the importance and application of optical and electrochemical methods as well as their performance improvement using various methods for the detection of pathogenic bacteria. The application of advanced nanomaterials including hyper branched nanopolymers, carbon‐based materials and silver, gold and so on. nanoparticles for biosensing of pathogenic...

article

Thrombolytic Agents: Nanocarriers in Controlled Release

Soodabeh Hassanpour, Han‐Jun Kim, Arezoo Saadati, Peyton Tebon, more

Small > 16 > 40 > n/a - n/a

Thrombosis is a life‐threatening pathological condition in which blood clots form in blood vessels, obstructing or interfering with blood flow. Thrombolytic agents (TAs) are enzymes that can catalyze the conversion of plasminogen to plasmin to dissolve blood clots. The plasmin formed by TAs breaks down fibrin clots into soluble fibrin that finally dissolves thrombi. Several TAs have been developed...

article

Sensitive monitoring of riboflavin in commercial multivitamins using poly (chitosan)‐based nanocomposite

Soodabeh Hassanpour, Arezoo Saadati, Mohammad Hasanzadeh

Journal of Molecular Recognition > 33 > 2 > n/a - n/a

The rapid and sensitive determination of riboflavin (RF) is important for the treatment of seborrheic and glossitis dermatitis, sunlight sensitivity, mucosal, and skin disorders. In this work, an electrochemical sensor was developed by electrodes modification using poly (chitosan) to sensitive detection of RF in commercial multivitamin. Electrodeposition of chitosan on the surface of glass carbon...

article

Proline dehydrogenase-entrapped mesoporous magnetic silica nanomaterial for electrochemical biosensing of L-proline in biological fluids

Mohammad Hasanzadeh, Arezoo Saadati Nahar, Soodabeh Hassanpour, Nasrin Shadjou, more

Enzyme and Microbial Technology > 2017 > 105 > C > 64-76

In this work, physical adsorption was used for immobilization of proline dehydrogenase onto a magnetic mesoporous silica nanomaterial. The immobilization and electrocatalytical activity of proline dehydrogenase entrapped in a magnetic mesoporous silica nanomaterial was studied using cyclic voltammetry, differential pulse voltammetry, and square wave voltammetry. The magnetic mesoporous silica networks...

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