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AimSystemic sclerosis (SSc) is characterized by immune abnormalities, progressive fibrosis of the skin and internal organs, and microvascular injury and damage. Interleukin‐21 receptor (IL‐21R) is expressed in the epidermis from patients with SSc. However, information describing the role of IL‐21 in SSc is limited.
MethodsWe established a mouse model of bleomycin (BLM)‐induced fibrosis. The frequency...
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