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Redistribution of selenium and manganese in postmitotic tissues of alpha-lipoic acid-supplemented aged rats has been proposed to contribute to metal-catalyzed protein oxidation. dl-Alpha-lipoic acid (LA) (100mg/[kg body wt.day]) was administered intraperitoneally to the Sprague–Dawley rats for 14 days. Serum selenium levels were lowered in the aged rats with LA supplementation compared with those...
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